Department of Computer and Information Technology (C&IT)
College of Technology

Graduate Studies in C&IT

Purdue University, West Lafayette, Indiana

Professional Interests:

Dr. Kane’s professional interests involve aspects of genomics, biomedical informatics, healthcare technology, and higher education. His professional experience includes preclinical research in the pharmaceutical industry, Vice President of R&D at a publicly-traded genomics/biotechnology company, and co-founding biotechnology companies based on technology and methods that he developed/patented. His primary interests have involved the development and utilization of genomic detection technologies, primarily DNA microarray methods, which have been applied to exploratory discovery efforts in agricultural, ecological, preclinical and clinical studies. His paper on the genomic and algorithmic methods for DNA probe design in DNA microarray detection has been cited by over 500 articles, has been internationally adopted as a standard method for DNA probe design and sequence analysis in genomics (referred to as “Kane’s criteria” or “Kane’s parameters”), and is the most common method utilized by commercial DNA microarray probe design software systems. In addition, he has led the efforts to develop data management tools in support of pharmacogenomics and personalized medicine, which have been extensively utilized as a teaching tool for healthcare professionals, and serves as the basis for a seed-stage healthcare data management company (Genomic Guidance, LLC). Dr. Kane also serves as an expert witness in criminal cases involving DNA evidence.

He serves as a co-founder and co-inventor for an auto-aiming broadband wireless antenna company (Broadband Antenna Tracking Systems, Inc). These entrepreneurial experiences have provided Dr. Kane the opportunity to provide valued interactions with many seed-stage technology companies in various capacities (scientific advisor, business plan development and review, patent portfolio development, etc.). In addition, Dr. Kane is the first professor at Purdue to construct an all-electric, street-legal vehicle through the conversion of a Volkswagen Beetle (personal project in his garage), which has led to participation on several grants and projects involved in the development of electric vehicle research and education.

Genomics and Personalized Medicine

Dr. Kane's team has developed an online education
and training tool in support of pharmacogenomics
and personalized medicine called Genescription,
funded by a grant from Microsoft External Research. This is a free, online software system available for anyone to utilize.

Functional Genomics

Collaborating with other scientists at Purdue University, genomic detection systems have been developed and utilized that detect changes in the regulation of genes in agricultural, ecological and microbial organisms.

Electric Vehicles

Dr. Kane converted a 1973 Volkswagen to an electric vehicle, and also lead the effort to build an electric go-kart to compete in the inaugural Purdue EVGrand Prix.

Technology Entrepreneurship

Dr. Kane is a co-founder Broadband Antenna Tracking Systems, Inc., which is commercializing innovative wireless technology developed at Purdue University. In addition, he is co-founder of Genomic Guidance, LLC., which is commercializing technology developed at Purdue University to facilitate the utilization of clinical genotyping in support of therapeutic decision support in healthcare.

DNA Forensics

Dr. Kane serves as a consultant and expert witness in criminal cases and litigation involving DNA evidence. This includes case work as well as instruction for professionals in the legal community that want to know more about the role of human genomics in forensics.

Raabe College of Pharmacy, Ohio Northern University

Dr. Kane is serving as a Visiting Research Scientist at the Raabe College of Pharmacy at Ohio Northern University. In this role he is working with ONU Pharmacy faculty to develop a world-class education and training program in personalized medicine and pharmacogenomics for pharmacy students, as well as practicing pharmacists.